HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethylamine → N-cyano-N'-ethyl-N"-[2-(2-thiazolylmethylthio)ethyl]guanidine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethylamine | HCID 6341 | — |
| Reactant | 2-[(Thiazol-2-yl)methylthio]ethylamine | HCID 12923403 | — |
| Reactant | N-cyano-N'-[2-(2-thiazolylmethyl-thio)ethyl]-S-methylisothiourea | HCID 20427996 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | N-cyano-N'-ethyl-N"-[2-(2-thiazolylmethylthio)ethyl]guanidine | HCID 54127424 | — |
Reaction Steps
Reaction of N-cyano-N'-[2-(2-thiazolylmethylthio)ethyl]-S-methylisothiourea, prepared by reacting 2-[(2-aminoethyl) thiomethyl]thiazole with dimethyl-N-cyanoimidothio carbonate in ethanol by the procedure of Example 97, with ethylamine in ethanol under reflux for 8 hours gives N-cyano-N'-ethyl-N"-[2-(2-thiazolylmethylthio)ethyl]-guanidine.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04000302 |
| Source dataset | uspto-grants-1976_12 |
| ORD ID | ord-668816c6aceb49feb6379be9678be2c3 |
| Source note | uspto-grants-1976_12 |