Acetic Anhydride → HCID 54293767, compound

HRID 1974662Notes

Reaction equation

HRID 1974662 reaction equation
[CH2:1]1[C:6]2[CH:7]=[C:8]([C:14]([OH:16])=[O:15])[C:9]([C:11]([OH:13])=O)=[CH:10][C:5]=2[CH2:4][CH2:3][O:2]1.C(OC(=O)C)(=O)C>>[CH2:1]1[C:6]2[CH:7]=[C:8]3[C:14](=[O:15])[O:16][C:11](=[O:13])[C:9]3=[CH:10][C:5]=2[CH2:4][CH2:3][O:2]1

Participants

3

Reactant 2

HCID 7918Acetic AnhydrideHCID 19101930HCID 19101930, compound

Product 1

HCID 54293767HCID 54293767, compoundYield 82.7%

Conditions

Temperature
100 °C

Procedure

A mixture of 3,4-dihydro-1H-2-benzopyran-6,7-dicarboxylic acid (7.28 g, 32.8 mmol) and acetic anhydride is stirred for 3.5 hours at 100° C., allowed to stand overnight at room temperature and filtered. The filter cake is washed with ether and dried to give the title product as a white solid (5.53 g, 82.7%). Recrystallization gives mp 156°-158° C.

Workup

  1. waitto stand overnight at room temperature
  2. filtrationfiltered
  3. washThe filter cake is washed with ether
  4. customdried

Sources & evidence

ORD record
ord-9a39aa8c0b7f4be5aed65be0600d9d3c
Source dataset
uspto-grants-1994_02
Patent number
US05283335

Reaction notes

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