Acetic Anhydride → HCID 53977713, compound

HRID 1974665Notes

Reaction equation

HRID 1974665 reaction equation
[N:1]1[C:10]2[C:5](=[C:6]([C:14]([OH:16])=[O:15])[C:7]([C:11]([OH:13])=O)=[CH:8][CH:9]=2)[CH:4]=[CH:3][CH:2]=1.C(OC(=O)C)(=O)C>>[N:1]1[C:10]2[C:5](=[C:6]3[C:14](=[O:15])[O:16][C:11](=[O:13])[C:7]3=[CH:8][CH:9]=2)[CH:4]=[CH:3][CH:2]=1

Participants

3

Reactant 2

HCID 7918Acetic AnhydrideHCID 19101925Quinoline-5,6-dicarboxylic acid

Product 1

HCID 53977713HCID 53977713, compoundYield 82.4%

Conditions

Temperature
0 °C

Procedure

A mixture of 5,6-quinolinedicarboxylic acid and acetic anhydride is stirred for 2 hours at reflux temperature, cooled to 0° C. and filtered. The filter cake is dried to give the title product as yellow needles (1.50 g, 82.4%) mp 247°-50° C., identified by H1NMR spectroscopy.

Workup

  1. temperatureat reflux temperature
  2. filtrationfiltered
  3. customThe filter cake is dried

Sources & evidence

ORD record
ord-0c67958822a44bf687ff642494df1b41
Source dataset
uspto-grants-1994_02
Patent number
US05283335

Reaction notes

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