Nitric Acid → 7-Nitro-1,2,3,4-tetrahydroquinoline

HRID 1974785Notes

Reaction equation

[NH:1]1[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[CH2:4][CH2:3][CH2:2]1.S(=O)(=O)(O)O.[N+:16]([O-])([OH:18])=[O:17]>>[N+:16]([C:8]1[CH:9]=[C:10]2[C:5]([CH2:4][CH2:3][CH2:2][NH:1]2)=[CH:6][CH:7]=1)([O-:18])=[O:17]

Participants

Reactant 3

HCID 944Nitric Acid

HCID 1118Sulfuric Acid

HCID 694601,2,3,4-Tetrahydroquinoline

Product 1

HCID 2525137-Nitro-1,2,3,4-tetrahydroquinoline

Procedure

nitrating 1,2,3,4-tetrahydroquinoline in the presence of sulfuric acid and nitric acid to obtain 7-nitro-1,2,3,4-tetrahydroquinoline;

Sources & evidence

ORD record: ord-bf8840da02a84da4a7e05cb95e8d70cb
Source dataset: uspto-grants-1994_02
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05283336

Reaction notes

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