Hydrazine → 1,2,3,4-Tetrahydroquinolin-7-amine

HRID 1974786Notes

Reaction equation

HRID 1974786 reaction equation

[N+:1]([C:4]1[CH:13]=[C:12]2[C:7]([CH2:8][CH2:9][CH2:10][NH:11]2)=[CH:6][CH:5]=1)([O-])=O.NN>[Ni]>[NH2:1][C:4]1[CH:13]=[C:12]2[C:7]([CH2:8][CH2:9][CH2:10][NH:11]2)=[CH:6][CH:5]=1

Participants

4

Reactant 2

HCID 9321Hydrazine

HCID 2525137-Nitro-1,2,3,4-tetrahydroquinoline

Product 1

HCID 152196191,2,3,4-Tetrahydroquinolin-7-amine

Reagents, catalysts & solvents 1

HCID 935NickelCatalyst

Procedure

reducing 7-nitro-1,2,3,4-tetrahydroquinoline in the presence of Raney nickel and hydrazine to obtain 7-amino-1,2,3,4-tetrahydroquinoline;

Sources & evidence

ORD record: ord-ca816a81f7f34cf79674be7ffa6c54e4
Source dataset: uspto-grants-1994_02
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05283336

Reaction notes

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