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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 197479Generated: October 30, 2026

Bromide ion → 4-[4'-[(Difluoromethyl)thio][1,1'-biphenyl]-4-yl]-2-(2,6-difluorophenyl)-4,5-dihydrooxazole

https://huagongshe.com/reaction/197479

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBromide ionHCID 259—
ReactantSodium ionHCID 923—
ReactantHydroxideHCID 961—
ReactantWaterHCID 962—
ReactantTolueneHCID 1140—
ReactantDiethyl EtherHCID 3283—
ReactantTetrabutylammoniumHCID 16028—
ReactantN-[2-chloro-1-[4'-[(difluoromethyl)thio][1,1'-biphenyl]-4-yl]ethyl]-2,6-difluorobenzamideHCID 18786412—
Product4-[4'-[(Difluoromethyl)thio][1,1'-biphenyl]-4-yl]-2-(2,6-difluorophenyl)-4,5-dihydrooxazoleHCID 15452584—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (6/10)
ORD IDord-7edeba6903804a6e818cc49aa2db4e34
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (6/10)