反应详情

温度

70 °C

A mixture of N-phenyl-1-naphthylamine (63 g, 0.29 mol) and 1.4-dibromobut-2-ene (12 g, 0.056 mol) is heated to 70° C. for three days. The resulting reaction mass is allowed to cool and is then extracted with 3×100 ml of hot hexane. The combined hexane extracts are concentrated in vacuo to an oil which is chromatographed (silica gel. 95/5 cyclohexane/diethyl ether) to give an oil. Said oil is then crystallized from ether to give 4.8 g (17.5% yield) of the title compound as a tan solid melting at 140°-142° C.

1. customThe resulting reaction mass
2. temperatureto cool
3. extractionis then extracted with 3×100 ml of hot hexane
4. concentrationThe combined hexane extracts are concentrated in vacuo to an oil which
5. customis chromatographed (silica gel. 95/5 cyclohexane/diethyl ether)
6. customto give an oil
7. customis then crystallized from ether