反应详情

10.2 g (53.9 mmol) of 5-benzyl-5-aza-1-oxaspiro[2,4]heptane are added dropwise to 60 ml of aqueous ethylamine solution (50%) and the mixture is stirred overnight at room temperature. The batch is then concentrated and the residue is distilled.

1. concentrationThe batch is then concentrated
2. distillationthe residue is distilled