Ethylamine → HCID 14578462, compound

HRID 1974866Notes

Reaction equation

HRID 1974866 reaction equation
[O:1]1[C:3]2([CH2:8][CH2:7][CH2:6][N:5]([C:9]([O:11][CH3:12])=[O:10])[CH2:4]2)[CH2:2]1.[CH2:13]([NH2:15])[CH3:14]>>[CH2:13]([NH:15][CH2:2][C:3]1([OH:1])[CH2:8][CH2:7][CH2:6][N:5]([C:9]([O:11][CH3:12])=[O:10])[CH2:4]1)[CH3:14]

Participants

3

Reactant 2

HCID 6341EthylamineHCID 19382148HCID 19382148, compound

Product 1

HCID 14578462HCID 14578462, compound

Procedure

9.3 g (54.3 mmol) of methyl 5-aza-1-oxaspiro[2,5]octane-5-carboxylate are added dropwise to 50 ml of ethylamine solution (50% strength in water) and the mixture is stirred overnight at room temperature. It is then concentrated and the residue is distilled.

Workup

  1. concentrationIt is then concentrated
  2. distillationthe residue is distilled

Sources & evidence

ORD record
ord-c21951e1571b416099283a1bdaf47d1f
Source dataset
uspto-grants-1994_02
Patent number
US05284842

Reaction notes

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