Sodium Methoxide → HCID 19382165, compound

HRID 1974877Notes

Reaction equation

HRID 1974877 reaction equation
[CH2:1]([N:8]1[CH2:14][CH2:13][C:10]2([O:12][CH2:11]2)[CH2:9]1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[CH3:15][O-:16].[Na+]>CO>[CH2:1]([N:8]1[CH2:14][CH2:13][C:10]([OH:12])([CH2:11][O:16][CH3:15])[CH2:9]1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

Participants

4

Reactant 2

HCID 10942334Sodium MethoxideHCID 111948055-Benzyl-1-oxa-5-azaspiro[2.4]heptane

Product 1

HCID 19382165HCID 19382165, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

26.8 g (0.14 mol) of 5-benzyl-1-oxa-5-azaspiro[2,4]heptane are heated overnight under reflux with 2.6 ml (14 mmol) of 30% strength sodium methoxide solution in 200 ml of absolute methanol. The product is concentrated and distilled.

Workup

  1. concentrationThe product is concentrated
  2. distillationdistilled

Sources & evidence

ORD record
ord-09004da01ed34976ba64bd891dcf6169
Source dataset
uspto-grants-1994_02
Patent number
US05284842

Reaction notes

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