HuagongsheHuagongshe Chemistry Print Report · For research reference only
Bromine → 6-Bromothieno[2,3-b]pyrazine-2,3(1H,4H)-dione
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Bromine | HCID 24408 | — |
| Reactant | Thieno[2,3-b]pyrazine-2,3(1H,4H)-dione | HCID 19100709 | — |
| Solvent | Acetic Acid | HCID 176 | — |
| Product | 6-Bromothieno[2,3-b]pyrazine-2,3(1H,4H)-dione | HCID 19100754 | 91% |
Reaction Steps
Thieno[2,3-b]pyrazine-2,3(1H,4H)-dione (0.10 g, 0.59 mmol) was reacted with bromine (0.095 g, 0.59 mmol) in acetic acid following the procedure outlined in example 3 (Method E). Yield 0.132 g (91%) of the title compound. M.p. >300° C. 1H-NMR (DMSO-D6, δ): 6.87 (s, 1H), 12.05 (s, 2H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05284847 |
| Source dataset | uspto-grants-1994_02 |
| ORD ID | ord-28d514c129234c1a9940c131fb6374d6 |
| Source note | uspto-grants-1994_02 |