Sulfuryl chloride → HCID 19100775, compound

Participants

Reaction Steps

A solution of 7-ethylthieno[2,3-b]pyrazine-2,3(1H,4H)-dione (1.0 g, 5.1 mmol) in 250 ml of acetic acid was stirred in a dry nitrogen atmosphere and sulphuryl chloride (0.41 ml, 5.1 mmol) was added dropwise. Stirring was continued for 1 h, the precipitate was filtered off, washed with water and dried at 100° C. under reduced pressure (30 Torr). Yield 0.77 g (65%) of the title compound. M.p. 282°-284° C. 1H-NMR (DMSO-D6, δ): 1.05 (t, 3H), 2.65 (q, 2H), 12.02 (s, 1H), 12.19 (s, 1H).

Provenance & Evidence