Diethyl Oxalate → HCID 19100721, compound

Participants

Reaction Steps

A mixture of di-t-butyl 4-cyclohexylthiophene-2,3-dicarbamate (400 mg, 1mmol), diethyl oxalate (5 ml, 37 mmol) and glacial acetic acid (5 ml) was refluxed for 16 h. The precipitate was filtered off and washed with glacial acetic acid to give 60 mg (24%) of the title compound. M.p.>270° C. 1H-NMR (DMSO-d6, δ): 1.1-1.9 (m, 10H), 2.75 (m, 1H), 6.7 (s, 1H), 11.9 (s, 1H), 12.25 (s, 1H).

Provenance & Evidence