Methyl iodide → HCID 19075352, compound

HRID 1975107Notes

Reaction equation

HRID 1975107 reaction equation
[CH3:1][I:2].[CH2:3]([O:7][C:8]1[C:9]([C:13]2[CH:14]=[N:15][CH:16]=[CH:17][CH:18]=2)=[N:10][S:11][N:12]=1)[C:4]#[C:5][CH3:6]>CC(C)=O>[I-:2].[CH2:3]([O:7][C:8]1[C:9]([C:13]2[CH:14]=[N+:15]([CH3:1])[CH:16]=[CH:17][CH:18]=2)=[N:10][S:11][N:12]=1)[C:4]#[C:5][CH3:6]

Participants

4

Reactant 2

HCID 6328Methyl iodideHCID 19075318HCID 19075318, compound

Product 1

HCID 19075352HCID 19075352, compound

Reagents, catalysts & solvents 1

HCID 180AcetoneSolvent

Procedure

A mixture of methyl iodide (0.5 ml, 7.5 mmol) and 3-(4-(2-butynyloxy)-1,2,5-thiadiazol-3-yl) pyridine (578 mg, 2.5 mmol) in acetone (5 ml) was stirred at room temperature for 18 h. The title compound precipitated from the solution and was collected by filtration to yield 0.88 g (95%).

Workup

  1. customThe title compound precipitated from the solution
  2. filtrationwas collected by filtration
  3. customto yield 0.88 g (95%)

Sources & evidence

ORD record
ord-32d084c46efa40649b2b488a16c7159a
Source dataset
uspto-grants-1994_02
Patent number
US05284859

Reaction notes

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