Hexylamine → HCID 15180169, compound

HRID 1975161Notes

Reaction equation

HRID 1975161 reaction equation
Cl[C:2]1[C:3]([C:7]2[CH:8]=[N:9][CH:10]=[CH:11][CH:12]=2)=[N:4][S:5][N:6]=1.[CH2:13]([NH2:19])[CH2:14][CH2:15][CH2:16][CH2:17][CH3:18]>CS(C)=O>[CH2:13]([NH:19][C:2]1[C:3]([C:7]2[CH:8]=[N:9][CH:10]=[CH:11][CH:12]=2)=[N:4][S:5][N:6]=1)[CH2:14][CH2:15][CH2:16][CH2:17][CH3:18]

Participants

4

Reactant 2

HCID 8102HexylamineHCID 104881643-Chloro-4-(pyridin-3-yl)-1,2,5-thiadiazole

Product 1

HCID 15180169HCID 15180169, compound

Reagents, catalysts & solvents 1

HCID 679Dimethyl SulfoxideSolvent

Procedure

A solution of 3-(4-chloro-1,2,5-thiadiazol-3-yl)pyridine (0.59 g, 3 mmol) and hexylamine (1.52 g, 15 mmol) in DMSO (5 ml) was heated at 100° C. for 48 h. After evaporation, water was added to the residue and extracted with ether. The combined organic extracts were dried and evaporated to give the title compound.

Workup

  1. customAfter evaporation, water
  2. additionwas added to the residue
  3. extractionextracted with ether
  4. customThe combined organic extracts were dried
  5. customevaporated

Sources & evidence

ORD record
ord-c3511f4e0749456ab5cf7903428e2273
Source dataset
uspto-grants-1994_02
Patent number
US05284859

Reaction notes

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