Piperidine → HCID 178447991, compound

Participants

Reaction Steps

0.078 mol of anhydrous sodium sulfate and 0.086 mol of piperidine were mixed and treated dropwise at -5° C. under nitrogen with 0.039 mol of trans-4-propylcyclohexylacetaldehyde. The reaction mixture was stirred at room temperature for 24 hours. Subsequently the precipitate was filtered off and washed with hexane. Distillation of the combined filtrates under a vacuum gave 1-[2-(trans-4-propylcyclohexyl)vinyl]piperidine of b.p. 118°-120° C./1 Torr in 75% yield.

Provenance & Evidence