Sulfuric Acid → Phthalide

HRID 1975305Notes

Reaction equation

HRID 1975305 reaction equation
[CH2:1]=[CH:2][CH:3]=[CH2:4].[C:5]([C:13]1C=CC=[CH:15][CH:14]=1)(=[O:12])C1C=CC=CC=1.S(=O)(=O)(O)[OH:20]>C(O)(=O)C>[C:5]1([C:13]2[C:2](=[CH:3][CH:4]=[CH:15][CH:14]=2)[CH2:1][O:20]1)=[O:12]

Participants

5

Reactant 3

HCID 1118Sulfuric AcidHCID 3102BenzophenoneHCID 78451,3-Butadiene

Product 1

HCID 6885Phthalide

Reagents, catalysts & solvents 1

HCID 176Acetic AcidSolvent

Procedure

Then, one mol of the butadiene derivative and one mol of a benzophenone derivative (compound of the following formula (X)) are condensated under the presence of a dehydrating agent such as anhydrous acetic acid, polyphosphoric acid or sulfuric acid to obtain a phthalide compound represented by the general formula (I) as substantially colorless crystals. ##STR10##

Sources & evidence

ORD record
ord-cdffaf0df831476883adfb90213023fe
Source dataset
uspto-grants-1994_02
Patent number
US05286702

Reaction notes

Loading…