HuagongsheHuagongshe Chemistry Print Report · For research reference only
Iodoethane → HCID 53799998, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Iodoethane | HCID 6340 | — |
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | Benzoic acid, 4-[(mercaptoacetyl)amino]- | HCID 745787 | — |
| Solvent | Water | HCID 962 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | HCID 53799998 | HCID 53799998 | — |
Reaction Steps
15 g of 4-mercaptoacetylaminobenzoic acid are dissolved in 450 ml of tetrahydrofuran, and 39.2 g of potash and 17.24 ml of ethyl iodide in 50 ml of tetrahydrofuran are added thereto. The mixture is stirred overnight and 200 ml of water and a small amount of 2N NaOH are added thereto. The cloudy solution is filtered, and the filtrate is acidified with concentrated HCl. The yellow crystals are filtered off with suction and recrystallised from isopropanol, yielding 4-ethylmercaptoacetylaminobenzoic acid having a melting point of 209°-211°.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05286728 |
| Source dataset | uspto-grants-1994_02 |
| ORD ID | ord-ac82c8f059ae41a4ac262b559f3f22e0 |
| Source note | uspto-grants-1994_02 |