反应详情

In a manner analogous to that described in Example 23, 1-{4-[N-(2-isopropyloxyethyl)-N-acetylamino]benzoyl}-4-[2-(4-chlorophenyl)ethyl]piperazine hydrochloride having a melting point of 142°-144° is obtained from 3 g of 1-{4-[N-(2-isopropyloxyethyl)amino]benzoyl}-4-[2-(4-chlorophenyl)ethyl]piperazine by reaction with acetyl chloride.