HuagongsheHuagongshe Chemistry Print Report · For research reference only
Cinnamylpiperazine → 1-{4-[N-(2-isopropyloxyethyl)-N-chloroacetylamino]benzoyl}-4-[3-phenylprop-2-enyl]piperazine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Cinnamylpiperazine | HCID 86803 | — |
| Reactant | 4-[N-(2-isopropyloxyethyl)-N-chloroacetylamino]benzoyl chloride | HCID 19099416 | — |
| Product | 1-{4-[N-(2-isopropyloxyethyl)-N-chloroacetylamino]benzoyl}-4-[3-phenylprop-2-enyl]piperazine | HCID 53715629 | — |
Reaction Steps
Analogously to Example 55, 1.5 g of 4-[N-(2-isopropyloxyethyl)-N-chloroacetylamino]benzoyl chloride are reacted with 0.81 g of cinnamylpiperazine (Example 27), yielding 1-{4-[N-(2-isopropyloxyethyl)-N-chloroacetylamino]benzoyl}-4-[3-phenylprop-2-enyl]piperazine. The hydrochloride thereof melts at 188°-190°.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05286728 |
| Source dataset | uspto-grants-1994_02 |
| ORD ID | ord-1cee9295272f40ef99918333ca19ab31 |
| Source note | uspto-grants-1994_02 |