1-[2-(4-Chlorophenyl)ethyl]piperazine → HCID 53987173, compound

HRID 1975386Notes

Reaction equation

HRID 1975386 reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([CH2:8][CH2:9][N:10]2[CH2:15][CH2:14][NH:13][CH2:12][CH2:11]2)=[CH:4][CH:3]=1.[Cl:16][CH2:17][C:18]([NH:20][C:21]1[CH:31]=[CH:30][C:24]([CH:25]=[CH:26][C:27](Cl)=[O:28])=[CH:23][CH:22]=1)=[O:19]>>[Cl:16][CH2:17][C:18]([NH:20][C:21]1[CH:31]=[CH:30][C:24]([CH:25]=[CH:26][C:27]([N:13]2[CH2:12][CH2:11][N:10]([CH2:9][CH2:8][C:5]3[CH:6]=[CH:7][C:2]([Cl:1])=[CH:3][CH:4]=3)[CH2:15][CH2:14]2)=[O:28])=[CH:23][CH:22]=1)=[O:19]

Participants

3

Reactant 2

HCID 122357141-[2-(4-Chlorophenyl)ethyl]piperazineHCID 54327961HCID 54327961, compound

Product 1

HCID 53987173HCID 53987173, compound

Procedure

Analogously to Example 7, 1-[2-(4-chlorophenyl)ethyl]piperazine and 4-chloroacetylaminocinnamic acid chloride are reacted to form 1-{3-[4-(N-chloroacetylamino)phenyl]prop-2-en-1-on-yl}-4-[2-(4-chlorophenyl)ethyl]piperazine.

Sources & evidence

ORD record
ord-38f8510ce0e94f08a6df80ed02fbea80
Source dataset
uspto-grants-1994_02
Patent number
US05286728

Reaction notes

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