2-(6-Methoxynaphthalen-2-yl)propan-1-ol → 2-(6-Methoxy-2-naphthyl)propionic acid

Participants

Reaction Steps

To a solution of 0.21 g 2-(6-methoxy-2-naphthyl)propan-1-ol in 2 ml of carbon tetrachloride, 2 ml acetonitrile, 3 ml of water, and 0.877 g of sodium metaperiodate is added 5 mg of ruthenium trichloride hydrate. After 4 hours at ambient temperature the mixture is extracted with 4 portions of 10 ml of methylene chloride. The combined organic extracts are dried over MgSO4, filtered, and concentrated to give the product 2-(6-methoxy-2-naphthyl)propionic acid.

Provenance & Evidence