HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 54439581, compound → (E)-3-[4-(1-imidazolylmethyl)phenyl]-2-propen-1-yl methyl 1,4-dihydro-2,6-dimethyl-4-(2-cyanophenyl)p-yridine-3,5-dicarboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 54439581 | HCID 54439581 | — |
| Reactant | 3-[4-(1-Imidazolylmethyl)phenyl]-2-propen-1-yl 3-aminocrotonate | HCID 86747583 | — |
| Solvent | Toluene | HCID 1140 | — |
| Product | (E)-3-[4-(1-imidazolylmethyl)phenyl]-2-propen-1-yl methyl 1,4-dihydro-2,6-dimethyl-4-(2-cyanophenyl)p-yridine-3,5-dicarboxylate | HCID 21650187 | — |
Reaction Steps
297 mg (1 mM) of 3-[4-(1-imidazolylmethyl)phenyl]-2-propen-1-yl 3-aminocrotonate and 229 mg (1 mM) of methyl 2-(2-cyanobenzylidene)acetoacetate were dissolved in 5 ml of toluene and refluxed for six hours. After cooling, the crystals produced were filtered off and recrystallized from methanol whereby the captioned compound was obtained. The yield was 402 mg (79.1%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05286869 |
| Source dataset | uspto-grants-1994_02 |
| ORD ID | ord-a2d347eb341c46aa8f7d823b55c4a32d |
| Source note | uspto-grants-1994_02 |