HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Phenylprop-2-En-1-Ol → (-)-4-(3-azidophenyl)-I,4-dihydro-2,6-dimethylpyridine-3,5-dicarboxylic acid monomethyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Phenylprop-2-En-1-Ol | HCID 308 | — |
| Reactant | 2-Methoxyethanol | HCID 8019 | — |
| Reactant | 3-[4-(1,2,4-Triazole-1-yl-methyl) phenyl]-2-propen-1-ol | HCID 54108898 | — |
| Reactant | 3-{4-[(Pyridin-3-yl)methyl]phenyl}prop-2-en-1-ol | HCID 54420190 | — |
| Reactant | 3-[4-(1,2,3,4-Tetrazole-1-yl-methyl)phenyl]-2-propen-1-ol | HCID 54512216 | — |
| Reactant | 3-[4-(I-imidazolylmethyl)phenyl]-2-propen-1-ol | HCID 70047020 | — |
| Solvent | Ethanol | HCID 702 | — |
| Solvent | Methanol | HCID 887 | — |
| Solvent | 1-Propanol | HCID 1031 | — |
| Solvent | Isopropanol | HCID 3776 | — |
| Product | (-)-4-(3-azidophenyl)-I,4-dihydro-2,6-dimethylpyridine-3,5-dicarboxylic acid monomethyl ester | HCID 131718339 | — |
Reaction Steps
Specific examples of the alcohol derivative of formula (II-2) for use in the present invention are methanol, ethanol, n-propanol, isopropanol, 2-methoxyethanol, cinnamyl alcohol, 3-[4-(I-imidazolylmethyl)phenyl]-2-propen-1-ol, 3-[4-(3-pyridylmethyl)phenyl]-2-propen-1-ol, 3-[4-(1,2,4-triazole-1-yl-methyl) phenyl]-2-propen-1-ol, 3-[4-(1,2,3,4-tetrazole-1-yl-methyl)phenyl]-2-propen-1-ol, 3-[5-(1-imidazolylmethyl)furan]-2-propen-1-ol, and 5-[4-(1-imidazolylmethyl)furan]-2,4-pentadiene-1-ol.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05286869 |
| Source dataset | uspto-grants-1994_02 |
| ORD ID | ord-4a9c588be8f04c4f93e37ad0938e316e |
| Source note | uspto-grants-1994_02 |