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HRID1975904

反应详情

EQUATION

反应方程式

HRID 1975904 的结构方程式

REACTANTS

反应物

3
结构：CC(C)(C)OC(=O)N[C@@H](CCCNC#N)C(=O)OC(C)(C)C
HCID11141515

未命名化合物

结构：CC(C)(C)OC(=O)N[C@@H](CCCNCOC=N)C(=O)OC(C)(C)C.Cl
HCID86583874

未命名化合物

结构：CC(C)(C)OC(=O)[C@@H](N)CCCNC#N
HCID86756654

未命名化合物

PRODUCTS

生成物

1
结构：CCON=CNCCC[C@H](NC(=O)OC(C)(C)C)C(=O)OC(C)(C)C.Cl
HCID178475096

未命名化合物

收率 75%

PROCEDURE

实验过程

By a method described above for the preparation of N2-(tert-butoxycarbonyl)-N5-(iminomethoxymethyl)-L-ornithine tert-butyl ester hydrochloride, 1.05 g (3.35 mmol) of N2-(tert-butoxycarbonyl)-N5-cyano-L-ornithine tert-butyl ester produced 0.95 g (75%) N2-(tert-butoxycarbonyl)-N5-(ethoxyiminomethyl)-L-ornithine tert-butyl ester hydrochloride (TLC, silica gel, methanol:dichloromethane/1:4, Rf=0.61) and 1.195 g (3.2 mmol) of N2-tert-butoxycarbonyl)-N5-cyano-L-ornithine tert-butyl ester produces 0.63 g (63%) N2-(tert-butoxycarbonyl)-N5-(iminoisopropoxymethyl)-L-ornithine tert-butyl ester hydrochloride (TLC, silica gel, methanol:dichloro methane/1:4, Rf=0.53). Mass Spectrum (CI) 360 (MH+, 100%).