Cyclohexyl isothiocyanate → HCID 11078720, compound

HRID 1975936Notes

Reaction equation

HRID 1975936 reaction equation
Cl.[NH2:2][C:3]1[CH:7]=[C:6]([Cl:8])[S:5][C:4]=1[S:9]([NH2:12])(=[O:11])=[O:10].[CH:13]1([N:19]=[C:20]=[S:21])[CH2:18][CH2:17][CH2:16][CH2:15][CH2:14]1>>[NH2:2][C:3]1[CH:7]=[C:6]([Cl:8])[S:5][C:4]=1[S:9]([NH:12][C:20]([NH:19][CH:13]1[CH2:18][CH2:17][CH2:16][CH2:15][CH2:14]1)=[S:21])(=[O:10])=[O:11]

Participants

3

Reactant 2

HCID 14289Cyclohexyl isothiocyanateHCID 688206263-Amino-5-chlorothiophene-2-sulfonamide hydrochloride

Product 1

HCID 11078720HCID 11078720, compound

Procedure

The title compound was prepared from 3-amino-5-chlorothiophene-2-sulfonamide hydrochloride and cyclohexyl isothiocyanate by a procedure analogous to the procedure described in example 3-a (yield 78%); 1H-NMR (DMSO-d6): δ1.1-1.9 (m, 10H), 4.0 (m, 1H), 6.45 (br s, 2H), 6.66 (s, 1H), 8.05 (br d, 1H), 11.2 (br s, 1H).

Sources & evidence

ORD record
ord-0ddf7b37bed34630b5781d719901e559
Source dataset
uspto-grants-2001_05
Patent number
US06225310B1

Reaction notes

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