2-Vinylpyridine → HCID 70244917, compound

HRID 1975975Notes

Reaction equation

HRID 1975975 reaction equation
[NH:1]1[C:9]2[C:4](=[CH:5][C:6]([NH:10][C:11]3[C:20]4[C:15](=[CH:16][CH:17]=[C:18](I)[CH:19]=4)[N:14]=[CH:13][N:12]=3)=[CH:7][CH:8]=2)[CH:3]=[CH:2]1.[CH:22]([C:24]1[CH:29]=[CH:28][CH:27]=[CH:26][N:25]=1)=[CH2:23]>>[NH:1]1[C:9]2[C:4](=[CH:5][C:6]([NH:10][C:11]3[C:20]4[C:15](=[CH:16][CH:17]=[C:18]([CH:23]=[CH:22][C:24]5[CH:29]=[CH:28][CH:27]=[CH:26][N:25]=5)[CH:19]=4)[N:14]=[CH:13][N:12]=3)=[CH:7][CH:8]=2)[CH:3]=[CH:2]1

Participants

3

Reactant 2

HCID 75212-VinylpyridineHCID 15521320HCID 15521320, compound

Product 1

HCID 70244917HCID 70244917, compound

Procedure

The title compound was prepared according to the method in Example 6 using (1H-Indol-5-yl)-(6-iodo-quinazolin-4-yl)-amine (200 mg, 0.52 mmol) and 2-vinylpyridine (65 mg, 67 uL, 0.62 mmol).

Sources & evidence

ORD record
ord-a43735aec0264a65abd10c9a2ddbeb89
Source dataset
uspto-grants-2001_05
Patent number
US06225318B1

Reaction notes

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