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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1976002Generated: October 30, 2026

Ethyl 1-benzylpiperazine-2-carboxylate → HCID 22721873, compound

https://huagongshe.com/reaction/1976002

Reaction equation

Participants

RoleNameHCIDCharge
ReactantEthyl 1-benzylpiperazine-2-carboxylateHCID 10682021—
Reactant1-(4-Pyridinyl)-4-piperidinecarbonyl chlorideHCID 11183700—
ProductHCID 22721873HCID 2272187367%

Reaction Steps

Using an analogous procedure to that described in Example 1, 1-(4-pyridyl)piperidine-4-carbonyl chloride was reacted with ethyl 1-benzylpiperazine-2-carboxylate (Helv. Chim. Acta, 1962, 45, 2383) to give 1-benzyl-2-ethoxycarbonyl-4-[1-(4-pyridyl)piperidin-4-ylcarbonyl]-piperazine in 67% yield.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06225309B1
Source datasetuspto-grants-2001_05
ORD IDord-300f3947aa74418991346a79d3319dea
Source noteuspto-grants-2001_05