Methyl 4-aminobutanoate → HCID 22721952, compound

HRID 1976005Notes

Reaction equation

HRID 1976005 reaction equation
[CH:1]1[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[CH:4]=[CH:3][C:2]=1[S:11]([NH:14][CH2:15][C:16]([OH:18])=O)(=[O:13])=[O:12].[NH2:19][CH2:20][CH2:21][CH2:22][C:23]([O:25][CH3:26])=[O:24]>>[CH:1]1[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[CH:4]=[CH:3][C:2]=1[S:11]([NH:14][CH2:15][C:16]([NH:19][CH2:20][CH2:21][CH2:22][C:23]([O:25][CH3:26])=[O:24])=[O:18])(=[O:12])=[O:13]

Participants

3

Reactant 2

HCID 18614Methyl 4-aminobutanoateHCID 70248192740-48-2

Product 1

HCID 22721952HCID 22721952, compoundYield 56%

Procedure

Using an analogous procedure to that described in the first paragraph of the portion of Example 30 which is concerned with the preparation of starting materials, N-(2-naphthylsulphonyl)glycine was reacted with methyl 4-aminobutyrate to give methyl 4-[2-(2-naphthalenesulphonamido)acetamido]butyrate in 56% yield.

Sources & evidence

ORD record
ord-3d402aa12b354cd7a24fae3fa5c28326
Source dataset
uspto-grants-2001_05
Patent number
US06225309B1

Reaction notes

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