HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-(4-Pyridinyl)-4-piperidinecarbonyl chloride → 3-Methyl-1-(2-naphthylsulphonyl)-4-[1-(4-pyridyl)piperidin-4-ylcarbonyl]piperazine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-(4-Pyridinyl)-4-piperidinecarbonyl chloride | HCID 11183700 | — |
| Reactant | 3-Methyl-1-(2-naphthylsulphonyl)piperazine | HCID 22721939 | — |
| Product | 3-Methyl-1-(2-naphthylsulphonyl)-4-[1-(4-pyridyl)piperidin-4-ylcarbonyl]piperazine | HCID 21999978 | 32% |
Reaction Steps
Using an analogous procedure to that described in Example 1, 1-(4-pyridyl)piperidine-4-carbonyl chloride was reacted with 3-methyl-1-(2-naphthylsulphonyl)piperazine to give 3-methyl-1-(2-naphthylsulphonyl)-4-[1-(4-pyridyl)piperidin-4-ylcarbonyl]piperazine in 32% yield;
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06225309B1 |
| Source dataset | uspto-grants-2001_05 |
| ORD ID | ord-37a082afa2674f41bbc7dec4d2c7f90c |
| Source note | uspto-grants-2001_05 |