HuagongsheHuagongshe Chemistry Print Report · For research reference only
Glycine methyl ester → HCID 22721845, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Glycine methyl ester | HCID 69221 | — |
| Reactant | HCID 11114582 | HCID 11114582 | — |
| Product | HCID 22721845 | HCID 22721845 | 76% |
Reaction Steps
Using an analogous procedure to that described in Example 20, 4-(6-bromonaphth-2-ylsulphonyl)-2-carboxy-1-[1-(4-pyridyl)piperidin-4-ylcarbonyl]piperazine was reacted with glycine methyl ester to give 4-(6-bromonaphth-2-ylsulphonyl)-2-[N-(methoxycarbonylmethyl)carbamoyl]-1-[1-(4-pyridyl)piperidin-4-ylcarbonyl]piperazine in 76% yield as a glass;
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06225309B1 |
| Source dataset | uspto-grants-2001_05 |
| ORD ID | ord-bbe743988d0f4aaeb46c547144f20ed5 |
| Source note | uspto-grants-2001_05 |