Water → (4-Thioureido-benzyl)-carbamic Acid Tert-butyl Ester

Participants

Reaction Steps

To a stirred solution of tert-butyl N-(4-{[(benzoylamino)carbothioyl]amino}benzyl)carbamate 10.4 g, 27.0 mmol) in MeOH (150 ml) (not completely dissolved) was added a solution of K2CO3 (8.5 g, 61.5 mmol) in circa. 15 ml water. The solution was stirred at room temperature for 24 hours and filtered to remove a white precipitate. The filtrate was evaporated in vacuo to yield 100% (7.6 g) of an off-white solid.

Provenance & Evidence