HCID 54538528, compound → HCID 53864393, compound

Participants

Reaction Steps

A solution of 1-(tert-butyloxycarbonyl)-4-{[(2,5-dichlorophenyl)methyl]piperid-1-yl}hexahydro4 H-azepine (700 mg, 1.58 mmol) in trifluoroacetic acid (2 ml) and methylene chloride (0.5 ml) was stirred at room temperature for 15 min. The solution was concentrated in vacuo and the residue was dissolved in chloroform and extracted with saturated aqueous sodium carbonate. The chloroform extract was dried over sodium sulfate and concentrated in vacuo to give 4-{[(2,5-dichlorophenyl)methyl]piperid-1-yl}hexahydro-4 H-azepine (489 mg, 90%).

Provenance & Evidence