D-Proline → HCID 28119401, compound

HRID 1976219Notes

Reaction equation

HRID 1976219 reaction equation
[NH:1]1[CH2:8][CH2:7][CH2:6][C@@H:2]1[C:3]([OH:5])=[O:4].F[C:10]1[CH:15]=[CH:14][CH:13]=[CH:12][C:11]=1[N+:16]([O-:18])=[O:17]>>[N+:16]([C:11]1[CH:12]=[CH:13][CH:14]=[CH:15][C:10]=1[N:1]1[CH2:8][CH2:7][CH2:6][C@@H:2]1[C:3]([OH:5])=[O:4])([O-:18])=[O:17]

Participants

3

Reactant 2

HCID 8988D-ProlineHCID 738951-Fluoro-2-nitrobenzene

Product 1

HCID 28119401HCID 28119401, compoundYield 82.3%

Procedure

The same procedures used in Reference Example 1 were repeated except for using D-proline and 1-fluoro-2-nitrobenzene to give the title compound. Yield 82.3%.

Sources & evidence

ORD record
ord-1d0ad3f6d386421a971aff8bf17743c3
Source dataset
uspto-grants-2001_05
Patent number
US06225306B1

Reaction notes

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