反应详情

To a solution of 6.4 g of (2S)-1-(2-nitrobenzoyl) proline methyl ester in 250 ml of methanol, there was added 1.5 g of a 10% palladium-carbon catalyst and then the resulting mixture was stirred at room temperature for 6 hours in a hydrogen gas atmosphere. The catalyst present in the reaction solution was filtered off and the filtrate was concentrated under reduced pressure to give 3.8 g (yield 75.2%) of the title compound as white crystals.

1. filtrationThe catalyst present in the reaction solution was filtered off
2. concentrationthe filtrate was concentrated under reduced pressure