HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-[[2-(4-Tolyl)benzoyl)amino]benzoic acid → (3aR)-5-[4-[[2-(4-Tolyl) Benzoyl]Amino]Benzoyl]-1,2,3,3a,4,5-Hexahydro-Pyrrolo[1,2-a]Quinoxaline
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-[[2-(4-Tolyl)benzoyl)amino]benzoic acid | HCID 15545382 | — |
| Reactant | (R)-1,2,3,3A,4,5-hexahydropyrrolo[1,2-a]quinoxaline | HCID 40639603 | — |
| Product | (3aR)-5-[4-[[2-(4-Tolyl) Benzoyl]Amino]Benzoyl]-1,2,3,3a,4,5-Hexahydro-Pyrrolo[1,2-a]Quinoxaline | HCID 20651246 | 31.7% |
Reaction Steps
The same procedures used in Example 1 were repeated using (3aR)-1,2,3,3a,4,5-hexahydro-pyrrolo[1,2-a]quinoxaline prepared in Reference Example 15 and 4-[[2-(4-tolyl)benzoyl)amino]benzoic acid to give the title compound after recrystallization from ethyl acetate-hexane. Yield 31.7%.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06225306B1 |
| Source dataset | uspto-grants-2001_05 |
| ORD ID | ord-0d24624d497648cb84c93371dde97147 |
| Source note | uspto-grants-2001_05 |