4-[(2-phenylbenzoyl)amino]benzoic Acid → HCID 20651243, compound

HRID 1976247Notes

Reaction equation

HRID 1976247 reaction equation
[OH:1][C@H:2]1[CH2:14][N:5]2[C:6]3[C:11]([NH:12][CH2:13][C@H:4]2[CH2:3]1)=[CH:10][CH:9]=[CH:8][CH:7]=3.[C:15]1([C:21]2[CH:38]=[CH:37][CH:36]=[CH:35][C:22]=2[C:23]([NH:25][C:26]2[CH:34]=[CH:33][C:29]([C:30](O)=[O:31])=[CH:28][CH:27]=2)=[O:24])[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=1>>[OH:1][C@H:2]1[CH2:14][N:5]2[C:6]3[C:11]([N:12]([C:30](=[O:31])[C:29]4[CH:28]=[CH:27][C:26]([NH:25][C:23](=[O:24])[C:22]5[CH:35]=[CH:36][CH:37]=[CH:38][C:21]=5[C:15]5[CH:16]=[CH:17][CH:18]=[CH:19][CH:20]=5)=[CH:34][CH:33]=4)[CH2:13][C@H:4]2[CH2:3]1)=[CH:10][CH:9]=[CH:8][CH:7]=3

Participants

3

Reactant 2

HCID 105435024-[(2-phenylbenzoyl)amino]benzoic AcidHCID 45115777HCID 45115777, compound

Product 1

HCID 20651243HCID 20651243, compoundYield 53.1%

Procedure

The same procedures used in Example 1 were repeated using (2R, 3aR)-2-hydroxy-1,2,3,3a,4,5-hexahydro-pyrrolo[1,2-a]quinoxaline prepared in Reference Example 17 and 4-[(2-phenylbenzoyl)amino]benzoic acid to give the title compound after recrystallization from ethyl acetate-hexane. Yield 53.1%.

Sources & evidence

ORD record
ord-332c918e4d4b462dadad1749ad56ba4b
Source dataset
uspto-grants-2001_05
Patent number
US06225306B1

Reaction notes

Loading…