4-[(2-phenylbenzoyl)amino]benzoic Acid → HCID 70245362, compound

HRID 1976250Notes

Reaction equation

HRID 1976250 reaction equation
[Si:1]([O:8][C@H:9]1[CH2:18][N:17]2[C@H:11]([CH2:12][NH:13][C:14]3[CH:23]=[CH:22][CH:21]=[CH:20][C:15]=3[C:16]2=[O:19])[CH2:10]1)([C:4]([CH3:7])([CH3:6])[CH3:5])([CH3:3])[CH3:2].[C:24]1([C:30]2[CH:47]=[CH:46][CH:45]=[CH:44][C:31]=2[C:32]([NH:34][C:35]2[CH:43]=[CH:42][C:38]([C:39](O)=[O:40])=[CH:37][CH:36]=2)=[O:33])[CH:29]=[CH:28][CH:27]=[CH:26][CH:25]=1>>[Si:1]([O:8][C@H:9]1[CH2:18][N:17]2[C@H:11]([CH2:12][N:13]([C:39](=[O:40])[C:38]3[CH:37]=[CH:36][C:35]([NH:34][C:32](=[O:33])[C:31]4[CH:44]=[CH:45][CH:46]=[CH:47][C:30]=4[C:24]4[CH:25]=[CH:26][CH:27]=[CH:28][CH:29]=4)=[CH:43][CH:42]=3)[C:14]3[CH:23]=[CH:22][CH:21]=[CH:20][C:15]=3[C:16]2=[O:19])[CH2:10]1)([C:4]([CH3:7])([CH3:5])[CH3:6])([CH3:3])[CH3:2]

Participants

3

Reactant 2

HCID 105435024-[(2-phenylbenzoyl)amino]benzoic AcidHCID 70245767HCID 70245767, compound

Product 1

HCID 70245362HCID 70245362, compoundYield 95%

Procedure

The same procedures used in Example 25 were repeated using (2R, 11aS)-2-(tert-butyldimethylsilyloxy)-1,2,3,10,11,11a-hexahydro-5H-pyrrolo [2,1-c][1,4]benzodiazepin-5-one prepared in Reference Example 26 and 4-[(2-phenylbenzoyl)amino]benzoic acid to give the title compound. Yield 95%.

Sources & evidence

ORD record
ord-a0a104bea98a47fcac0db9f1a0eda639
Source dataset
uspto-grants-2001_05
Patent number
US06225306B1

Reaction notes

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