4-[(2-phenylbenzoyl)amino]benzoic Acid → HCID 12042763, compound

HRID 1976252Notes

Reaction equation

HRID 1976252 reaction equation
[CH2:1]1[C@@H:5]2[CH2:6][NH:7][C:8]3[CH:15]=[CH:14][CH:13]=[CH:12][C:9]=3[C:10](=[O:11])[N:4]2[CH2:3][CH2:2]1.[C:16]1([C:22]2[CH:39]=[CH:38][CH:37]=[CH:36][C:23]=2[C:24]([NH:26][C:27]2[CH:35]=[CH:34][C:30]([C:31](O)=[O:32])=[CH:29][CH:28]=2)=[O:25])[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=1>>[C:16]1([C:22]2[CH:39]=[CH:38][CH:37]=[CH:36][C:23]=2[C:24]([NH:26][C:27]2[CH:28]=[CH:29][C:30]([C:31]([N:7]3[C:8]4[CH:15]=[CH:14][CH:13]=[CH:12][C:9]=4[C:10](=[O:11])[N:4]4[CH2:3][CH2:2][CH2:1][C@@H:5]4[CH2:6]3)=[O:32])=[CH:34][CH:35]=2)=[O:25])[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=1

Participants

3

Reactant 2

HCID 105435024-[(2-phenylbenzoyl)amino]benzoic AcidHCID 44430445(11aR)-1,2,3,10,11,11a-Hexahydro-5H-pyrrolo[2,1-c][1,4]benzodiazepin-5-one

Product 1

HCID 12042763HCID 12042763, compoundYield 43%

Procedure

The same procedures used in Example 25 were repeated using (11aR)-1,2,3,10,11,11a-hexahydro-5H-pyrrolo[2,1-c][1,4]benzodiazepin-5-one prepared in Reference Example 25 and 4-[(2-phenylbenzoyl)amino]benzoic acid to thus give the title compound. Yield 43.0%.

Sources & evidence

ORD record
ord-0daa44aa55ac464c92035b06176d9a3e
Source dataset
uspto-grants-2001_05
Patent number
US06225306B1

Reaction notes

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