HuagongsheHuagongshe Chemistry Print Report · For research reference only
Butyl bromide → 3-(n-butylamino)phenol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Butyl bromide | HCID 8002 | — |
| Reactant | 3-Aminophenol | HCID 11568 | — |
| Reactant | Sodium Bicarbonate | HCID 516892 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | 3-(n-butylamino)phenol | HCID 11126626 | 57% |
Reaction Steps
One-tenth mol of m-aminophenol in 150 ml methanol is treated with 0.11 mol of n-butyl bromide and 0.1 mol of NaHCO3 and the mixture is heated under reflux for 5 h. After cooling, the reaction mixture is filtered and the solvent removed under reduced pressure. The residual oil is vacuum fractionated to give 3-(n-butylamino)phenol.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06228977B1 |
| Source dataset | uspto-grants-2001_05 |
| ORD ID | ord-1fef69f2c82c4c429e9e3ab1bbd91205 |
| Source note | uspto-grants-2001_05 |