反应详情

A solution of methyl 5-indole carboxylate (1.75 g, 10 mmol) and N-fluoro-2,4,6-trimethylpyridinium triflate (3.75 g, 13 mmol) in methanol (100 mL) was heated at reflux for 18 hours and concentrated. The concentrate was purified by flash column chromatography on silica gel to provide 200 mg of the desired product.

1. temperatureat reflux for 18 hours
2. concentrationconcentrated
3. customThe concentrate was purified by flash column chromatography on silica gel