HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Hydroxide → 4-(4-fluorophenoxy)benzenesulfonic Acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | 4-(4-Fluorophenoxy)benzenesulfonic acid 4-fluorophenyl ester | HCID 9928916 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 4-(4-fluorophenoxy)benzenesulfonic Acid | HCID 11022596 | 105.7% |
Reaction Steps
To a slurry of 47.43 g (0.131 mol) of 4-(4-fluorophenoxy)benzenesulfonic acid 4-fluorophenyl ester in 475 mL of ethanol was added 13.09 g (0.327 mol, 2.5 equivalents) of sodium hydroxide pellets. This mixture was heated at reflux for three hours and stirred overnight at room temperature. The resulting solids were filtered yielding 37.16 g (98%) of 4-(4-fluorophenoxy)benzenesulfonic acid, sodium salt.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06229025B1 |
| Source dataset | uspto-grants-2001_05 |
| ORD ID | ord-6d20346cfce94ee3b1567168dff3c29d |
| Source note | uspto-grants-2001_05 |