Sodium Methoxide → HCID 21999479, compound

HRID 1976932Notes

Reaction equation

[CH3:1][N:2]([CH3:14])[C:3]1[C:8]([F:9])=[CH:7][C:6]([N+:10]([O-:12])=[O:11])=[C:5](F)[CH:4]=1.[CH3:15][O-:16].[Na+]>>[CH3:1][N:2]([CH3:14])[C:3]1[C:8]([F:9])=[CH:7][C:6]([N+:10]([O-:12])=[O:11])=[C:5]([O:16][CH3:15])[CH:4]=1

Participants

Reactant 2

HCID 10942334Sodium Methoxide

HCID 21999572HCID 21999572, compound

Product 1

HCID 21999479HCID 21999479, compound

Procedure

2.0 g (10 mmol) of 4-dimethylamino-2,5-difluoronitrobenzene (18) is treated with sodium methoxide according to general method F to give Compound 19 after chromatography on silica gel.

Sources & evidence

ORD record: ord-9d29dfe25c904838a48a31428b9481ee
Source dataset: uspto-grants-2001_05
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06229055B1

Reaction notes

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