tert-Butylbenzoic acid (mixed isomers) → HCID 54500483, compound

HRID 1976986Notes

Reaction equation

HRID 1976986 reaction equation
[CH3:1][O:2][C:3](=[O:24])[C@H:4]([CH2:6][C:7]1[CH:12]=[CH:11][C:10]([NH:13][C:14]([C:16]2[C:21]([Cl:22])=[CH:20][CH:19]=[CH:18][C:17]=2[Cl:23])=[O:15])=[CH:9][CH:8]=1)[NH2:5].[CH3:25][C:26]([C:29]1[CH:37]=[CH:36][CH:35]=[CH:34][C:30]=1[C:31](O)=[O:32])([CH3:28])[CH3:27]>>[CH3:1][O:2][C:3](=[O:24])[C@H:4]([CH2:6][C:7]1[CH:8]=[CH:9][C:10]([NH:13][C:14]([C:16]2[C:21]([Cl:22])=[CH:20][CH:19]=[CH:18][C:17]=2[Cl:23])=[O:15])=[CH:11][CH:12]=1)[NH:5][C:31]([C:30]1[CH:34]=[CH:35][CH:36]=[CH:37][C:29]=1[C:26]([CH3:28])([CH3:27])[CH3:25])=[O:32]

Participants

3

Reactant 2

HCID 136850tert-Butylbenzoic acid (mixed isomers)HCID 233839334-(2,6-Dichlorobenzoylamino)-L-phenylalanine methyl ester

Product 1

HCID 54500483HCID 54500483, compound

Procedure

4-[[(2,6-Dichlorophenyl)carbonyl]amino]-N-[[2-(1,1-dimethylethyl)phenyl]carbonyl]-L-phenylalanine methyl ester was prepared from 4-[[(2,6-dichlorophenyl)carbonyl]amino]-L-phenylalanine methyl ester and 2-(1,1-dimethylethyl)benzoic acid using the general procedure described in example 3. HR MS: Obs. mass. 527.1523. Calcd. mass. 527.1573 (M+H).

Sources & evidence

ORD record
ord-bc61e15d3bdf4102acbec833da94212c
Source dataset
uspto-grants-2001_05
Patent number
US06229011B1

Reaction notes

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