Hydrochloric Acid → HCID 178455760, compound

Participants

Reaction Steps

A mixture prepared by adding 5.9 g (29.5 mmol) of sodium benzenesulfinate dihydrate, 5 ml of 6N hydrochloric acid, and 40 ml of mixed solvent of toluene/ethanol (1/1) to 6.1 g (14.5 mmol) of the crude 4-(trans-4-(2-(trans-4-(trans-4-vinylcyclohexyl)cyclohexyl)vinyl)cyclohexyl)propylbenzene was refluxed for 40 hours. Water in an amount of 30 ml was added to the reaction mixture, extracted with 150 ml of toluene, washed with water thrice, and then dried over anhydrous magnesium sulfate. The solvent was distilled off under a reduced pressure and the residue was subjected to silica gel column chromatography (eluent: heptane/toluene=95/5) to obtain 3.8 g of a crude (E)-4-(trans-4-(2-(trans-4-(trans-4-vinylcyclohexyl)cyclohexyl)-vinyl)cyclohexyl)propylbenzene. This product was recrystallized from a mixed solvent of ethanol/ethyl acetate to obtain 1.1 g of the subjective compound.

Provenance & Evidence