HuagongsheHuagongshe Chemistry Print Report · For research reference only
Phenol → HCID 20654280, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Phenol | HCID 996 | — |
| Reactant | Chloropyrazine | HCID 73277 | — |
| Reactant | (Octahydro-1H-pyrido[1,2-A]pyrazin-7-YL)methanol | HCID 12985539 | — |
| Product | HCID 20654280 | HCID 20654280 | — |
Reaction Steps
A mixture of (7RS,9aSR)-7-hydroxymethyl-2,3,4,6,7,8,9,9a-octahydro-1H-pyrido[1,2-a]pyrazine (U.S. Pat. No. 5,326,874) and 2-chloropyrazine were combined according to Preparation 3. The product from this reaction was coupled with phenol according to Example 1 to give the title compound. mp (—HCl) 217-219° C. HRMS calcd for C19H24N4O: 324.1945, found: 324.1981.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06231833B1 |
| Source dataset | uspto-grants-2001_05 |
| ORD ID | ord-bcb367c8a025431bb03f0e6bf488b422 |
| Source note | uspto-grants-2001_05 |