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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1977060Generated: November 2, 2026

Hydrochloric Acid → HCID 20654261, compound

https://huagongshe.com/reaction/1977060

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantHCID 22940605HCID 22940605—
SolventDiethyl EtherHCID 3283—
SolventChloroformHCID 6212—
ProductHCID 20654261HCID 20654261—

Reaction Steps

A solution of 0.44 g (1.2 mmol) of (7S,9aR)-2-BOC-7-(4-fluorophenoxy)methyl-2,3,4,6,7,8,9,9a-octahydro-1H-pyrido[1,2-a]pyrazine in 25 mL of chloroform was treated with excess HCl(g) in ethyl ether and stirred at ambient temperature for 2 h. The solvent was evaporated to give 0.40 g of title compound as the dihydrochloride salt which was used for subsequent reactions without purification.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06231833B1
Source datasetuspto-grants-2001_05
ORD IDord-896f40811b7b43e9bee57ce3994b2c56
Source noteuspto-grants-2001_05