p-Chlorophenacyl bromide → HCID 4738722, compound

HRID 1977126Notes

Reaction equation

HRID 1977126 reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([C:8](=[O:17])[CH:9]([N:11]2[CH2:16][CH2:15][NH:14][CH2:13][CH2:12]2)C)=[CH:4][CH:3]=1.BrCC(C1C=CC(Cl)=CC=1)=O>>[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([C:8](=[O:17])[CH2:9][N:11]2[CH2:12][CH2:13][NH:14][CH2:15][CH2:16]2)=[CH:4][CH:3]=1

Participants

3

Reactant 2

HCID 68303p-Chlorophenacyl bromideHCID 10912032HCID 10912032, compound

Product 1

HCID 4738722HCID 4738722, compound

Procedure

4′-Chloro-2-(piperazin-1-yl)acetophenone was prepared as for 4′-chloro-2-(piperazin-1-yl)propiophenone except that commercially available 2-bromo-4′-chloroacetophenone (Aldrich, 10,127-3) is used instead of 2-bromo-4′-chloropropiophenone.

Sources & evidence

ORD record
ord-debcab856e8d46fbb1febbf03c55856d
Source dataset
uspto-grants-2001_05
Patent number
US06232314B1

Reaction notes

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