5-Fluoro-2-methyl-1-((4-(methylsulfinyl)phenyl)methylene)-1H-indene-3-acetic acid → 40796-29-0

HRID 1977193Notes

Reaction equation

HRID 1977193 reaction equation
[F:1][C:2]1[CH:3]=[C:4]2[C:8](=[CH:9][CH:10]=1)[C:7](=[CH:11][C:12]1[CH:17]=[CH:16][C:15]([S:18]([CH3:20])=[O:19])=[CH:14][CH:13]=1)[C:6]([CH3:21])=[C:5]2[CH2:22][C:23]([OH:25])=[O:24].C[O-].[Na+:28]>CO>[F:1][C:2]1[CH:3]=[C:4]2[C:8](=[CH:9][CH:10]=1)[C:7](=[CH:11][C:12]1[CH:17]=[CH:16][C:15]([S:18]([CH3:20])=[O:19])=[CH:14][CH:13]=1)[C:6]([CH3:21])=[C:5]2[CH2:22][C:23]([O-:25])=[O:24].[Na+:28]

Participants

4

Reactant 2

HCID 53525-Fluoro-2-methyl-1-((4-(methylsulfinyl)phenyl)methylene)-1H-indene-3-acetic acidHCID 10942334Sodium Methoxide

Product 1

HCID 5734979840796-29-0

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent2×

Procedure

5-fluoro-2-methyl-1-(ρ-methylsulfinylbenzylidene)-3-indenylacetic acid (1.79 g.) in methanol (10 ml.) is added to a solution of sodium methoxide (0.27 g.) in methanol (5 ml.). The reaction mixture is stirred for 20 minutes and evaporated to dryness to yield sodium 5-fluoro-2-methyl-1-(ρ-methylsulfinylbenzylidene)-3-indenylacetate.

Workup

  1. customevaporated to dryness

Sources & evidence

ORD record
ord-adc33654b86c433389231e36385caff9
Source dataset
uspto-grants-2001_05
Patent number
US06232312B1

Reaction notes

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