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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1977293Generated: October 31, 2026

HCID 54357020, compound → HCID 53724184, compound

https://huagongshe.com/reaction/1977293

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 54357020HCID 54357020—
ReactantHCID 178418361HCID 178418361—
CatalystPalladiumHCID 23938—
SolventMethanolHCID 887—
ProductHCID 53724184HCID 5372418461.9%

Reaction Steps

To a solution of 4-[4-(2-cyclohexenyloxy)piperidin-1-yl]benzoic acid ethyl ester (3.82 g) in methanol (80 ml) was added 10% palladium on carbon (1.0 g), and hydrogen gas at atmosphere pressure for 5 hours. The reaction mixture was filtered, and the filtrate was concentrated by evaporation under reduced pressure to give 4-(4-cyclohexyloxypiperidin-1-yl)benzoic acid ethyl ester (2.38 g).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06232290B1
Source datasetuspto-grants-2001_05
ORD IDord-fa8bd7ad6f9b48708eae403a4c4d53a8
Source noteuspto-grants-2001_05