HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 54357020, compound → HCID 53724184, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 54357020 | HCID 54357020 | — |
| Reactant | HCID 178418361 | HCID 178418361 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 53724184 | HCID 53724184 | 61.9% |
Reaction Steps
To a solution of 4-[4-(2-cyclohexenyloxy)piperidin-1-yl]benzoic acid ethyl ester (3.82 g) in methanol (80 ml) was added 10% palladium on carbon (1.0 g), and hydrogen gas at atmosphere pressure for 5 hours. The reaction mixture was filtered, and the filtrate was concentrated by evaporation under reduced pressure to give 4-(4-cyclohexyloxypiperidin-1-yl)benzoic acid ethyl ester (2.38 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06232290B1 |
| Source dataset | uspto-grants-2001_05 |
| ORD ID | ord-fa8bd7ad6f9b48708eae403a4c4d53a8 |
| Source note | uspto-grants-2001_05 |